A cancer of the white blood cells by completed preclinical work on it.

A cancer of the white blood cells – by completed preclinical work on it, it will be taken in a Phase I trial in approximately 20-40 patients with advanced B-cell lymphoma.

The trial will be managed by Cancer Research UK’s Drug Development Office and found in up to five4 hospitals throughout Britain.This impairs the symbiotic relationship between the hypoxia and well – oxygenated cancer cells and in two mouse models cancer has led to reduced tumor growth as the hypoxic tumor cells was deprived of glucose, and render the remaining cells are sensitive radiation. As MCT1 expression exclusively in hypoxic regions of human cancer biopsy specimens found, the authors propose to MCT1 is a potential new target for cancer therapeutics. In an accompanying Comment discusses Greg Semenza, more at Johns Hopkins University School of Medicine, in Baltimore, this concept as well as other therapeutic implications.

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